Fig. 6
From: Identification of RAG-like transposons in protostomes suggests their ancient bilaterian origin
Alignment of RAG2L sequences from protostomes and deuterostomes. RAG2L sequences are aligned and displayed as in Fig. 5. Domains, beta sheet regions of each kelch-type blade, the GG motif, secondary structure (helixes - wavy lines; beta sheet - arrows, other - straight line), protein-protein interactions (5 Å threshold) displayed above the alignment derive from the BbeRAG2L cryo-EM structure (PDB: 6B40). Sequences displayed are: BbeRAG2L_B (GenBank: KJ748699.1), PflRAG2L_B (TSA:GDGM01438088.1), SpuRAG2L_B_Ech1 (Uniprot: Q45ZT5) and CviRAG2L_B_Biv1_0007, PimRAG2L_B_Biv2_5135, and NgeRAG1L_D_2322 from this study (Additional file 7: Alignment S1b). These RAG2L proteins are the transposon pairs of the RAG1L sequences displayed in Fig. 5 except that PimRAG2L_B_Biv2_5135 was used instead of PimRAG2L_B_Biv2_3145 due to merge uncertainties in the 3145 sequence; these two sequences are 98% identical on their counterpart RAG1L core. Species abbreviations as in Fig. 5