Mobile DNA celebrates Transposon Day every June 16th, to commemorate the birthdate of the founder of transposable elements research, Barbara McClintock (1902-1992). This day was designated to honor her legacy and draw attention to the important research that has changed the way researchers think about evolution, disease, and genomics. Please check out our special page for a new quiz, a selection of our journal's best articles from the last 12 months, and much more!
Featured article: Dfam updated!
Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. This expansion demonstrates the utility of many of Dfam’s new features and provides insight into the long term challenges ahead for improving de novo generated transposable element datasets. Read it here!
Featured series: Transposable Elements in Model Organisms
We are proud to present a new series of review papers focused on transposable elements (TE) in model organisms. This series will deliver a comprehensive and even coverage of the diversity of TEs populating the model species; outstanding questions and future directions with the study of TEs in species; and much more!
Celebrate Transposon Day 2020 with Mobile DNA!
Featured review: transposable element landscapes in yeast models
Genomics and other large-scale analyses have drawn attention to the potential impacts of TEs on their host genomes. However, it remains challenging to transition from identifying potential roles to clearly demonstrating the level of impact TEs have on genome evolution and possible functions that they contribute to their host organisms. In this new review, author Patrick Maxwell summarizes TE content and distribution in four well-characterized yeast model systems in this review.
Featured Article
Comparative analysis on the expression of L1 loci using various RNA-Seq preparations
The role of DNA methylation in aging has been widely studied. However, epigenetic mutations, here defined as aberrant methylation levels compared to the distribution in a population, are less understood. For this Methodology, our authors developed whole-cell, cytoplasmic and nuclear RNA-Seq datasets from 22Rv1 prostate cancer cells to test the influence of different preparations on the quality and effort needed to measure L1 expression.
Call for Papers: Endogenous Retroviruses in Evolution and Disease
The Editors of Mobile DNA and Retrovirology extend an invitation to submit original research articles related to endogenous retroviruses to their new collection: Endogenous Retroviruses in Evolution and Disease.
Open for submissions: May 24, 2019
Closed for submissions: January 2021
Submit an article to Mobile DNA for the series.
Articles
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Transposable element-derived sequences in vertebrate development
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SeqURE – a new copy-capture based method for sequencing of unknown Retroposition events
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Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals
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Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element
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Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions
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The expanding universe of transposon technologies for gene and cell engineering
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Mobile DNA and evolution in the 21st century
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Mobilizing diversity: transposable element insertions in genetic variation and disease
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Characterization and potential functional significance of human-chimpanzee large INDEL variation
Review collection
All Reviews
Repository for all published Review articles. Contributions from some of the leading researchers working with mobile DNA.
Article collection
Mobile DNA Tools
Repository for all published articles on softwares, databases, and methodologies.
2020
Thematic series
Transposable Elements in Model Organisms
Edited by the Editors-in-Chief
2019
Thematic series
Endogenous Retroviruses in Evolution and Disease
Cross-journal series with Retrovirology. Edited by the Editors-in-Chief of Mobile DNA and Retrovirology.
Thematic series
Transposable Elements in Model Organisms (coming soon)
Edited by the Editors-in-Chief
2015
Thematic series
Keystone Symposium: Mobile Genetic Elements and Genome Evolution
Edited by: Henry Levin, Parmit Singh
2014
Review series
Mobile genetic elements in biotechnology
Edited by: Henry Levin, Thomas Eickbush, Marlene Belfort, Nancy Craig, Cedric Feschotte
2013
Review series
Mobile introns review series
Edited by: Thomas Eickbush, Marlene Belfort, Nancy Craig, Daniel Voytas
Pre-submission Inquiries
The Editors-in-Chief of Mobile DNA welcome authors to send any pre-submission inquiries they might have to the Editorial Email address, which can be found here by clicking on "Contact Us" (upper left side of page). We ask that you please include “Pre-submission inquiry” in the subject line of your email and that you include the title and abstract of your proposed submission within the message. Our Editors will do their best to respond to you in a timely manner.
Editors' Picks
Highlights from recent literature on mobile elements, selected by the Editors-in-Chief.
Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells. [Proc Natl Acad Sci U S A. 2020] PubMed
Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling [Mol Cell 2020] PubMed
Upregulation of a KN1 homolog by transposon insertion promotes leafy head development in lettuce. [Proc Natl Acad Sci U S A. 2020] PubMed
Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression. [Genes Dev. 2020] PubMed
Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals. [Mob DNA. 2020] PubMed
Editors-in-Chief
Irina Arkhipova, Marine Biological Laboratory at Woods Hole
Jeffrey Bennetzen, University of Georgia, USA
Kathleen Burns, Dana-Farber Cancer Institute at Harvard Medical School, USA
Pascale Lesage, INSERM, France
In 2019, we welcomed our new Associate Editors:
Orsolya Barabas, European Molecular Biology Laboratory (EMBL), Germany
Gael Cristofari, Institut National de la Santé et de la Recherche Médicale, France
Adam Ewing, Mater Research Institute-University of Queensland, Australia
Clément Gilbert, CNRS, Université Paris Saclay, France
Molly G Hammell, Cold Spring Harbor Laboratory, USA
Damon R Lisch, Purdue University, USA
Joe Peters, Cornell University, USA
Phoebe Rice, The University of Chicago, USA
Aims and scope
Mobile DNA is an online, peer-reviewed, open access journal that publishes articles providing novel insights into the function, biological impact, and evolution of transposable elements in any organism. Topics related to transposable elements may include genetic or epigenetic variation, genome rearrangements, mechanisms, patterns and processes of transposition, and the role of mobile elements in host genome evolution.
Mobile DNA aims to understand:- mechanisms of intra- and intergenomic mobility via genetic, comparative genomic, biochemical and structural approaches
- regulation of DNA rearrangements by the environment and during development
- how DNA restructuring reshapes cellular function and organism evolution
- the role of transposable elements in disease in a variety of organisms
- host—element interaction and genetic/epigenetic regulatory networks
Mobile DNA reflects the need for a journal that spans all aspects of specialized recombination, from structure and mechanism to evolutionary impact. In addition, the journal will consider articles on the utility of mobile genetic elements in biotechnological methods and protocols, and related biocomputational tools.
TE Digest
Updated monthly, check out the newest published research on transposable elements in the TE Digest on Alexander Suh of Uppsala University's Genomicrocosm page here.
Links to Useful TE Community Resources
Transposable elements labs directory
Women in TEs (maintained by Cedric Feschotte)
Job vacancies
Transposons Worldwide SLACK Page (Managed by Rebecca Berrens)
Mobile DNA Tools Collection
TE digest (Managed by Alexander Suh)
Forthcoming meetings
The ICTE 2020 meeting, which was scheduled to take place in St Malo in the spring and was cancelled due to the current pandemic, has been replaced by a series of virtual conferences (vICTE 2020). Conferences will be given every two weeks on Tuesday at 6:00 pm (French/CEST time) and will start September 8th. Please see here for more details.
4th Uppsala Transposon Symposium - 30th September - 2nd October 2020- Uppsala, Sweden
Follow
Annual Journal Metrics
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Speed
38 days to first decision for reviewed manuscripts only
33 days to first decision for all manuscripts
108 days from submission to acceptance
17 days from acceptance to publication
Citation Impact
3.161 - 2-year Impact Factor
5.173 - 5-year Impact Factor
0.958 - Source Normalized Impact per Paper (SNIP)
2.379 - SCImago Journal Rank (SJR)
Usage
180,324 Downloads
946 Altmetric Mentions
